BW 755C( —— )

Catalog No. M27503 CAS No. 66000-40-6

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

BW 755C
Note

Research use only, not for human use.
Brief Description

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
Description

BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.(In Vitro):BW 755C is approximately equipotent inhibitors of COX-1 and COX-2 in intact cells.
In Vitro

——
In Vivo

Animal Model:Immature Wistar rats ~22 days of age Dosage:0.03, 0.1, 0.3, 1.0, 3.1 and 10 mg/rat Administration:Subcutaneous injection, once Result:Reduced 5-HETE (moderately) and 12-HETE (strongly).
Synonyms

——
Pathway

Immunology/Inflammation
Target

Lipoxygenase
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

66000-40-6
Formula Weight

229.2
Molecular Formula

C10H10F3N3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (436.30 mM)
SMILES

NC(CC1)=NN1c1cccc(C(F)(F)F)c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chao W, et al. Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways. Sci Rep. 2019 Feb 20;9(1):2344.

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